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The highest frequency of symptomatic complicated cholelithiasis was among liraglutide and semaglutide users rather than dulaglutide users

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Clinical symptoms Type 1 diabetes has obvious clinical symptoms, such as polydipsia, polyuria, polyphagia, etc., that is, "3Ps", while type 2 diabetes often does not have obvious "3Ps" symptoms, so many patients with type 2 diabetes may be in an undetected state for a long time after the onset

this hypothesis is also given credence by the common finding of GSTP overexpression in tumor cell lines that are not drug resistant